Knowledge on Lyssavirus
The ASKLEPIOS consortium was funded by the European Commission, under the FP7 program. The goal of ASKLEPIOS was to identify rational targets for the development of novel therapeutic leads against rabies encephalitis by targeting both viral replication and the host response. Artemis was involved in the testing of several therapeutic candidates using in vitro and in vivo models. Assays such as neutralization tests, quantitative PCR and viral isolation were routinely used. In addition, the rabies mouse model was refined for studying therapeutic interventions.